Disorders that affect the heart or blood vessels are called cardiovascular disorders and can be of one of three types – Heart disorders, Peripheral blood vessel disorders and Cerebrovascular disorders.

Cardiovascular drugs affect the function of the heart in three main ways. When they work to control the force of contraction of the heart muscle it is called inotropic effects. When the drugs work to manipulate the frequency of the heartbeat it is said to cause a chronotropic effects and when they can affect the regularity of the heartbeat it is known as a rhythmic effect.

Inotropic agents influence the cardiac musclesin a positivemanner byincreasing the force of the heart’s contraction. This is doneby the inotropic agents binding to and inhibiting the action of a membrane enzyme that squeezes the sodium ions out of the cell interior. These drugs also amplify the release of calcium from internal stores, resulting in a rise in intracellular calcium.

Another type of inotropic agent called Dobutamineincreases contractility without affecting blood pressure or heart rate at all.

Aravis Pharmaceuticals has conducted extensive research over the last 3 decades to devise the highest quality cardiovascular drugs for supply to manufacturers worldwide. They are as follows: